Protandim® NAD Synergizer®

Formulated to target NAD, and has been shown to double sirtuin activity in 24 hours.

NAD Synergizer™

Vegan Vegetarian




Free from artificial colors, flavors, and sweeteners

Protandim® NAD Synergizer™

Protandim® NAD Synergizer™, is a natural supplement that can help enhance health and well-being. It boosts energy and helps you to focus more on the task at hand.


  • Supports healthy longevity and the removal of cellular waste (autophagy) *
  • Improves mental focus and concentration *
  • Supports positive mood and motivation *
  • Maintain existing healthy cholesterol levels and supports healthy vascular system *

How Much Does The LifeVantage Protandim® NAD Synergizer™ Cost?

Protandim NAD Synergizer is sold in a container with a content of 60 capsules. You can buy it depending on the area you are located. Check out our LifeVantage overview.

The pricing of the LifeVantage Protandim NAD Synergizer depends on the country, and the buying option. In the USA, you can buy it with a One-Time Order at the List Price of $59,99. Or, you can buy it with Subscribe & Save, cancel anytime, shipping discounts, and exclusive offers, for the price of $49,99. You can benefit from buying the LifeVantage Tri-Synergizer.

Revitalize with this 100% Sirtuin increase, Rivive your NAD to get More Concentration, Motivation, and energy.

What's Inside the Sirtuins Activator?

All about the LifeVantage Protandim NAD Synergizer ingredients.

Wasabi (Wasabia japonica) Rhizome Powder

Wasabi (Wasabia japonica) Rhizome Powder

Protandim® NAD Synergizer- Wasabi ingredient, rich in isothiocyanates, which have been shown to be potent activators of many different types of genetics and metabolic processes.*

Olive (Olea europaea) Leaf Extract

Olive (Olea europaea) Leaf Extract

Protandim® NAD Synergizer- Olive leaf extract ingredient, contains a nutrient shown to support healthy inflammation response, healthy cholesterol levels already within a normal range, and a healthy gut.*

Cuprous Niacin

Cuprous Niacin

Protandim® NAD Synergizer- Cuprous Niacin ingredient, contains a precursor for NAD synthesis and an essential cofactor for iron metabolism, nerve function, and energy production.*




Protandim® NAD Synergizer- Theacrine ingredient, similar to caffeine, has been used for 2,000 years to support liver, kidney, and gallbladder function, and studies suggest it supports healthy detoxification.*

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Healthy Longevity

Protandim® NAD Synergizer delivers whole-body benefits, such as support for healthy longevity and the body’s healthy inflammatory response, joint health, a healthy vascular system, and more. It also provides immediate benefits for energy, mood, and focus.

Immediate benefits for energy, mood, and focus

Protandim® NAD Synergizer - Sirtuins are the first comprehensive supplement to address all seven sirtuin pathways. With Protandim®, you can provide your body with the raw materials it needs to unleash its natural anti-aging power and help you sustain good health into old age. 

Protandim® NAD Synergizer™ Testimonials

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NAD Synergizer™ Usage

Directions: Take 2 capsules in the morning daily with food.
Warning: Not for use by individuals under the age of 18 years. Do not take if pregnant or nursing.
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Description text

What Is The Sirtuin Theory of Aging? Protandim NAD

NAD Synergizer™ Label Info

Sub Heading

Serving Size
2 Capsules
Servings Per Container
Per Serving Amount DV% **
Niacin 780mcg NE 5%
Copper 187mcg 21%
Proprietary Blend 462mg **
Wasabi Rhizome Powder
Olive Leaf Extract
Cuprous Niacin
Other Ingredients
Rice Flour, Hydroxypropyl Methylcellulose, Magnesium Stearate, Silicon Dioxide.

** % Daily Value are based on a 2,000 calorie diet.

NAD Synergizer™ FAQ

Description text

NAD is the abbreviation for Nicotinamide Adenine Dinucleotide

NAD is essential for sirtuin activity throughout the entire body and sirtuin activity declines with age. Protandim® NAD Synergizer TM supports the expression of genes that are part of signaling pathways to activate NAD-ependent enzymes and increase sirtuin activity. Therefore moving beyond NAD and into the real goal–sirtuin activity

Researchers and scientists agree that aging is the natural result of overall cellular deterioration. One major way this occurs is through exposure to free radicals, other oxidants, and toxicological insults. It is impossible to avoid these exposures because the food you eat, the air you breathe, our modern lifestyles, stress, and even exercise, but we can do certain things to maintain our health as we age. The human body naturally fights these insults by producing its own antioxidant and detoxification enzymes through Nrf2-dependent mechanisms.

However, as we grow older, Nrf2 works less efficiently. That’s where Protandim® Nrf2 Synergizer TM plays a critical role. It supports these Nrf2-dependent mechanisms to boost the body’s production of antioxidant and detoxification enzymes. Another natural phenomenon relating to the aging process is our mitochondria (the cell’s powerplant) begins working less efficiently. Less efficient mitochondria produce less energy and produce excess free radicals and other oxidants. Supporting overall mitochondrial function is important to promote overall health as we age.

Protandim NRF1 was designed to both increase mitochondrial number and provide ingredients shown to support mitochondrial health. Lastly, another major significant effect of the aging process is a decline of cellular NAD levels and reduction of sirtuin activity. Sirtuin activity has been shown to play a major roll in supporting overall health. Protandim® 
NAD Synergizer TM was designed to support NAD levels and sirtuin activity. Thus, taking the entire Protandim family of products will help support all of these significant aspects of the aging process.*

Protandim® NAD Synergizer TM combines Olive Leaf Extract, Wasabi Extract, Theacrine, Copper and Niacin in a unique proprietary blend.

Protandim Nrf2 and NRF1 Synergizers work together to reduce oxidative stress and support mitochondria biogenesis and function. With the addition of NAD Synergizer, we can now target other biochemical pathways known to support healthy aging and increased health span

Adults, take two capsules daily. Do not take within six hours of bedtime.

Please consult your physician if you are taking any medication before use.

No, we do not recommend this product if you are pregnant or nursing.

No, we do not recommend this product for children. Our products are made for individuals 18 years-of-age and older. This product should not be taken by children.

Yes, we perform exhaustive testing to verify that all LifeVantage products meet or exceed quality standards. The Quality Control measures implemented by LifeVantage exceed industry standards. We rigorously test every lot of product for identity, potency, microbial
contamination, pesticides and heavy metals, and physically audit manufacturing facilities and raw material suppliers.

No, the individual ingredients in Protandim NAD Synergizer aren’t as effective in supporting the expression of genes that are part of the signaling pathways to activate the NAD dependent enzymes as LifeVantage’s botanical blend.* For best results, it is recommended to take the entire Protandim line.

The raw ingredients are tested, carefully weighed out, blended and packed into capsules following strict Good Manufacturing Practices (GMP) guidelines. Every lot of finished Protandim NAD Synergizer is tested for compliance to approved specifications in addition to receiving a final quality inspection following dietary supplement regulations. Every lot must, meet or exceed established finished product specifications before it can be released by LifeVantage Quality Assurance.

All Protandim NAD Synergizer manufacturers are required to maintain a strict allergen program to protect against any potential cross contamination of allergens. These facilities are frequently audited to ensure that the processes and protocols are being strictly adhered to to ensure the safety of the product.

No, there are no dyes or food colorings in Protandim NAD Synergizer.

Protandim NAD Synergizer is 100% Vegetarian, free from gluten, wheat, dairy, gelatin and yeast. The ingredients in Protandim NAD Synergizer are naturally derived or bio-identical ingredients.

The FDA does not approve dietary supplements, however, companies must follow all regulations and submit a notification to the FDA within the first month of marketing a new product. Additionally, manufacturers and distributors must ensure all claims and information on the product label and any other labeling are truthful and not misleading. Under FDA regulations, all domestic and foreign companies that manufacture, package, label or hold dietary supplements, including those involved with testing, quality control, and dietary supplement distribution in the U.S., must comply with current Good Manufacturing Practices (cGMPs) for dietary supplements

Some of the active ingredients in Protandim NAD Synergizer are fat soluble, so taking Protandim NAD Synergizer with a meal containing some fat allows the ingredients to be absorbed more efficiently (but it’s not absolutely necessary)

The shelf life for Protandim NAD Synergizer is two years from the date of manufacture.

As with any supplement, particularly if you have a medical condition, are taking medication or other supplements, you should speak with your healthcare provider before taking Protandim NAD Synergizer. If you experience nausea, vomiting, diarrhea or any other difficulties after
taking Protandim NAD Synergizer, discontinue use and consult your healthcare provider.

Some Western diets are lacking in certain nutritional elements, so multivitamin supplementation may be beneficial for some people.

We do not expect there to be any side effects for the typical Protandim NAD Synergizer consumer. However, some individuals may have natural allergic responses or sensitivities to one or more of the ingredients, just as some people are allergic to pollen or penicillin. If you are
experiencing any adverse reaction, discontinue use of the product and call 1 (866) 460-7241

Yes, Protandim NAD Synergizer is Vegetarian.

Please, only use according to the directions on the label (two capsules per day).

More About NAD Synergizer™

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