NRF1 Synergizer™

The First Biohack to Fight Aging Harness the Youthful Energy of Mitochondria.

Protandim NRF1 Synergizer

Vegan Vegetarian




Free from artificial colors, flavors, and sweeteners

Protandim® NRF1 Synergizer™

Age-related declines in brain function and cognitive performance are inevitable, but with Protandim® NRF1 Synergizer™ they can be reversed.

Protandim® NRF1 Synergizer™ harnesses the youthful energy of mitochondria to boost brain health and cognitive performance.*


  • Improves performance through energy function*
  • Supports cellular health*
  • Increases cellular energy, or adenosine triphosphate (ATP)*

How Much Does The Lifevantage Protandim® NRF1 Synergizer™ Cost?

Protandim NRF1 Synergizer is sold in a container with a content of 60 capsules. You can buy it depending on the area you are located. Check out our LifeVantage overview.
The pricing of the LifeVantage Protandim NRF1 Synergizer depends on the country, and the buying option. In the USA, you can buy it with a One-Time Order at the List Price of $59,99. Or, you can buy it with Subscribe & Save, cancel anytime, shipping discounts, and exclusive offers, for the price of $49,99. You can benefit from buying the LifeVantage Dual Synergizer, or Tri-Synergizer.

Say NO to Aging and Get a Brain Boost, Protandim® NRF1 Synergizer™

What's Inside the Mitochondria Power Activator?

All about the LifeVantage Protandim NRF1 Synergizer ingredients.

Acetyl L Carnitine ingredient

Acetyl L-Carnitine

Protandim® NRF1 Synergizer™ - Acetyl L-Carnitine ingredient. An amino acid naturally produced in the body and, combined with alpha lipoic acid, boosts mitochondria production, supports healthy cellular aging, and protects against normal oxidation of RNA and mitochondria.*

Quercitin ingredient


Protandim® NRF1 Synergizer™ - Ingredient Quercetin is a polyphenol that helps to protect the mitochondria and their function, which supports ATP synthesis. Quercetin is a nutrient found in red apples, red onions, red grapes and other plant foods. Helps boost mitochondrial health and natural energy production.*

Alpha Lipoic Acid ingredient

Alpha-Lipoic Acid

Protandim® NRF1 Synergizer™ - ingredient Alpha-Lipoic Acid contributes to the maintenance of normal blood glucose levels. ALA is also a powerful antioxidant that has been proven to help protect the body from free radicals.*

Grape Extract ingredient

Grape Extract

Protandim® NRF1 Synergizer™ - Grape extract ingredient contains powerful natural stilbenoids (resveratrol and viniferin) which have been shown to support healthy aging by activating the NRF1 protein and other age-related cell-signaling pathways.*

Coenzyme Q10 ingredient

Coenzyme Q10

Protandim® NRF1 Synergizer™ - Coenzyme Q10 ingredient made in the body and plays a key role in ATP production and, combined with alpha lipoic acid, supports cellular energy levels, healthy stress response, and antioxidant defense mechanisms.*

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Power Up to Perform

The body's mitochondria naturally slow down as you age, but Protandim® NRF1 Synergizer™ uses natural ingredients to help keep your mitochondria youthful. This is a biohack for your brain health and cognitive performance.

The pathway to power

Protandim® NRF1 Synergizer™ is a supplement that can help you stay sharp, focused, and energetic. It helps slow down the aging process and increase longevity. All while boosting your brain health and cognitive performance.* 

Protandim® NRF1 Synergizer™ Testimonials

How She Suffered From Here Thyroid But Became a New Woman

From a thyroid sufferer to a new woman “So this may be a little long, but here goes, and I’m going to be writing this…

How This Mom Regained Her Energy, and Became More Productive

As a mother, it’s so easy to get your energy bank empty. And if you don’t refill it, you feel tired, frustrated, and even worthless.…

How I Manage My Back Injury and Live With Less Pain and Stiffness

” Thank you, Marge, for introducing me to the coaching. I used to take 2 Aleve every day before playing golf. My stiffness and pain…

Are You Tired Without an Obvious Cause?

A growing number of people suffer from persistent fatigue that won’t go away even if you take lots of rest. Long-term fatigue that stays even…

How She Got a Smooth Delivery and Healthy Baby Despite IURG

Wow! What a gift! This beautiful baby has been ACTIVATED even before Day one! Thank you so much for sharing your ACTIVATION pregnancy and delivery…

How Her Son Got a Strong Immune System After Suffering Years From Asthma, Allergies and Eczema

Thank you, for sharing Alice story and her son’s journey with Asthma and Food Allergies. My youngest son suffered (since 6 months old) asthma, allergies,…

How This Dry, Irritated, Flaky and Red Skin Went Away

Thanks to Kathy Kaymark, from a customer: Say what, GONE in 6 days. SIX DAYS. This is just one example of medical miracles I am…

What Biohacking Products Do We Offer?

Biohacking has become a very popular trend in recent years. What exactly does it mean? Is it really possible to hack our bodies? We have…

I Boosted My Body After Being Hit With Covid

This is what medical professional Scott Miller, PA of Miller Family Pediatrics, had to say last night. It was part of a fun, educational and…

How She Reversed Her Diabetes

Life is good! Thanks for the share. My daughter, Sira, was diagnosed with diabetes in the fall of 2019. Since then, she has been taking…

NRF1 Synergizer™ Usage

Directions: Take 2 capsules in the morning with food and a glass of water.
Warnings: Not for use by individuals under the age of 18 years. Do not take if pregnant or nursing.
Note: 100% Vegetarian. Gluten-free and dairy-free
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What Is The Mitochondrial Theory of Aging? NRF1 Synergizer™

NRF1 Synergizer™ Label Info

Serving Size

2 Capsules
Servings Per Container
Per Serving Amount DV% **
Proprietary Blend 790mg
Grape (Vitis Vinifera) Skin, Seed, Pulp Extract
Alpha Lipoic Acid
Enzyme Q10
Other Ingredients
Vegetable Capsule Hydroxypropyl Methylcellulose, Magnesium Stearate.

** % Daily Value are based on a 2,000 calorie diet.

† Daily Value (DV) not established.

NRF1 Synergizer™ FAQ

Like flipping a light switch, Protandim NRF1 Synergizer instructs your cells to produce more mitochondria. And that gives your cells the energy you need to feel more active, alert, and younger. While free radicals continue to break down mitochondria with every breath, Protandim NRF1 helps support the cellular process of building those powerhouses back up, which promotes cellular health and supports healthy aging.*

NRF1 stands for Nuclear Respiratory Factor 1. It should not be confused with NFE2L1 which is Nuclear factor erythroid 2 like-1.

Nutrigenomics is the study of how nutrition and naturally occurring compounds affect our genes and how they are expressed.

Mitochondrial biogenesis is the process by which newmitochondria are formed in the cell. Mitochondrial biogenesis is activated by numerous different signals during times of cellular stress or in response to environmental stimuli such as exercise.

Protandim® Nrf2 & NRF1 Synergizers use ingredients to reduce oxidative stress and support mitochondria production to increase cellular health and in turn, helps support healthy aging.

Take 2 capsules daily. For best results, take Protandim NRF1 at the same time each day

Please consult your physician if you are taking any medication before use.

No, we do not recommend this product if you are pregnant or nursing.

Although dietary supplement manufacturers must register their facilities with FDA, they are not required to get FDA approval before producing or selling dietary supplements. Manufacturers and distributors must ensure all claims and information on the product label, as well as any other labeling, are truthful and not misleading. Under FDA regulations, all domestic and foreign companies that manufacture, package, label or hold dietary supplements, including those involved with testing, quality control and dietary supplement distribution in the U.S., must comply with current Good Manufacturing Practices (cGMPs) for dietary supplements.

Protandim Nrf2 Synergizer can help your body:
• Reduce oxidative stress*
• Supports a healthy cellular response to normal aging, caused by oxidative stress*
• Activate Nrf2 protein to turn on natural antioxidant production*
• Supports normal cellular repair and rejuvenation*
• Protect cells from free radical damage*

Protandim NRF1 Synergizer is designed to:
• Increase cellular energy (ATP)*
• Improve performance through energy production*
• Enhance cellular health — cells function at peak performance*
• More mitochondria production and their ability to network*

A Activates NRF1 Protein

— Wakes up the NRF1 protein to support mitochondrial biogenesis

— the creation of new, large and elongated mitochondria that create a connected network inside the cell. The better the network is connected, the better the cell functions.*

B Boosts Mitochondria Production

— Means your body functions more efficiently: promotes normal cellular repair, supports heme production, supports brain function and cognitive health, and supports heart health.*

C Increases ATP

— Higher ATP levels increase the energy available to the cells of all your vital organs. This promotes peak functioning of body systems, especially those with high energy demands, such as the brain, heart and skeletal muscle.*

By helping to promote cell function by maintaining the health of the mitochondria.*

• Acetyl L-Carnitine - An amino acid (a building block for proteins) that is naturally produced in the body. Acetyl L-Carnitine enhances either mitochondrial DNA (mtDNA) transcription, the stability of mitochondrial mRNA, or mitochondrial protein synthesis. Combined with Alpha Lipoic Acid, these two ingredients boost mitochondria production, support healthy cellular aging, and protect against normal oxidation of RNA and mitochondria.*
• Coenzyme Q10 — It is made in the body and resides primarily in mitochondria where it plays a key role in transporting electrons so ATP is made. Combined with Alpha Lipoic Acid, it supports cellular energy levels, stress response and antioxidant defense mechanisms.*
• Alpha-lipoic acid — Alpha lipoic acid, or ALA, is made in the body and helps to turn glucose into energy that the cell can use. ALA is able to neutralize free radicals because of its -thiol groups because it is both fat and water soluble, it can protect all parts of the cell (including the mitochondria) from these free radicals.*
• Grape Extract — This extract, made from the whole grape (seeds, pulp and skin), contains powerful natural polyphenols (flavanols) known to support healthy aging. The bioactives help activate the NRF1 protein and other biological pathways to  aintain good health.*
• Quercetin — It is made in the body and resides primarily in mitochondria where it plays a key role in transporting electrons so ATP is made. Combined with Alpha Lipoic Acid, it supports cellular energy levels, stress response and antioxidant defense mechanisms.*

While there is no test at this time, LifeVantage is in the process on studying the effects of Protandim NRF1 Synergizer.

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