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Youthful energy of mitochondria.

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Repair and rejuvenate your cells.

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Double your sirtuin activity.

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LifeVantage Protandim

LifeVantage Protandim®, protected by U.S. patents, has multiple synergizers to improve your health.

On this page, you can read more about the Nrf1 Synergizer, Nrf2 Synergizer, the NAD Synergizer, the Dual Synergizer and Tri-Synergizer.


LifeVantage discovered that 5 key ingredients, when combined in the correct ratios, had the ability to decrease oxidative stress by an average of 40% in 30 days and restore antioxidant levels to those you’d expect to see in a 20-year-old. They named this breakthrough formula Protandim®, derived from “promoting the tandem” co-regulation of this powerful SOD and CAT duo.*


Protandim® isn’t a gimmick. In 2005, Protandim® was under investigation by ABC Primetime News investigating it as a potential scam in which they attempted to prove that the claims of the makers are false by conducting their own study. As it turns out, the show reported that after taking Protandim®, "the reporter's bloodwork showed a reduction of oxidative stress by 45% in just 2 weeks." Several studies were done after the series aired, and all concluded that Protandim® is effective at fighting off free radicals that can lead to oxidative stress and aging of our bodies. Interestingly enough, one study from Washington State University expressed "it is our opinion that raising Nrf2 is likely to be the most important health promoting approach into the foreseeable future."

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Nrf1 Synergizer™

Protandim® Nrf1 Synergizer™ uses nutrients to harness the youthful energy of mitochondria. An essential biohack for brain health and cognitive performance.*


  • Improves performance through energy function *
  • Supports cellular health*
  • Increases cellular energy, or adenosine triphosphate (ATP) *

Nrf2 Synergizer®

Protandim® Nrf2 Synergizer, protected by U.S. patents, is made of five potent botanicals.

Support your body’s own production of powerful antioxidants to fight the signs of aging.*


  • Reduces oxidative stress by 40% in just 30 days*
  • Helps the body detoxify genes, keeping the master blueprint of the cell’s function intact*
  • Significantly reduces cellular stress through Nrf2 activation*
  • Produces enzymes capable of neutralizing more than 1,000,000 free radicals*
  • Helps to regulate survival genes*
  • Supports the body's natural ability to repair and rejuvenate its own cells*
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NAD Synergizer™

Protandim® NAD Synergizer was specifically formulated to target NAD, and has been shown to double sirtuin activity in 24 hours. Supporting increased health, focus, energy, mental clarity, and mood.*


  • Supports healthy longevity and the removal of cellular waste (autophagy) *
  • Improves mental focus and concentration *
  • Supports positive mood and motivation *
  • Maintain existing healthy cholesterol levels and supports healthy vascular system *

Dual Synergizer™

Protandim Nrf2 & Nrf1 Synergizers* effectively reduce oxidative stress and support mitochondria function to fight the effects of aging.*


Protandim Nrf2, NAD, and Nrf1 Synergizers effectively reduce oxidative stress, support mitochondria function, increase sirtuin activity, and target cell signaling pathways to fight the effects of aging.

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